Is this question directed at me? Yes I had a Delta 10/10 and I used it with no hardware mixer as well. I had it set up as follows (from memory!)
Audio out --->>>>> Audio in Audio out
Virus 1 & 2 Delta 10/10 1 & 2 Delta 10/10 1 & 2 >> Monitor speakers!
In the software mixer section of the Delta 10/10 just make sure nothing is muted. I cant remember the specifics though.
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