Hey Mate,
I still run my interface out through my mixer. The fader on my mixer is in a convenient position for me to adjust monitoring volume, plus I use the VU/PPM's on the mixer to check that levels are good out of the box.
You could just run your monitors straight from the 800 though. Entirely up to you. Outputs 1/2 are usually what you'd use, I also have a pair of main outputs which mirror 1/2.
As far as running your synths straight into the RME, thats up to you too. I still run my synths through my mixer, others might not. I have all my synth connected to a patch bay. half normalled to the inputs on my mixer, and when I need to record them as audio I just patch them out of the patchbay into the interface.
RME make damn fine interfaces, and their converters are great. There are better out there of course, but you'll also be spending alot more. Dont worry about the gear regret...
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MYSPACE
G5, Cubase SX, Reason 2.5, Acess Virus RackXL, Yamaha Motif Rack, Yamaha CS-10, Roland D-50, Korg X5D, Korg Electribe ER-1mkII, HALion VST Sampler, MOTU 2408mkIII, Studer 169, Roland JUNO 60
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