Hiya,
I haven't got a TI myself, but I've just noticed in the TI Manual that you can select whether the TI uses its own internal clock or one over USB/spdif, or sync'd via a host.
http://access-music.de/pdffolder/Vir...al_english.pdf
Page 133.
Are they both set to the same frequencies, too?
Otherwise you could try connecting the Virus up to the s/pdif on the 0404. The PCI would stand to offer better latency than going into the M16DX and being transferred again over USB.
If all else fails I'd otherwise be tempted to use the TI's balanced analogue outputs into the M16DX mixer as it would retain the 24-bit/96KHz sound quality from the TI, but the added USB connection may increase latency a touch.
I'm unsure as to whether the TI can use VC over standard Midi. I only have an Indigo v1 myself, so I'm still in the dark ages using SoundDiver!
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PS > And another thing! Will the Ti|3 have user customisable/importable wavetables?
A ribbon-controller or XY-Pad might be nice, too, please! Thanks!