first of all, it's 16 parts, not voices ... and you can have 3 different stereo outputs.
there may be various ways to accomplish this, but i tend to adjust each
patch's volume while working with MIDI and then later bounce them to wave audio.
of course i keep the MIDI patterns, but muted (for further changed, that may occur).
panning i would do only on audio, because when you do that with VC: it's hard to do changes later.
bouncing to audio also makes sense, when patches have OSC phase init set to 0. this means
the Virus will gate the signal, instead of retriggering on MIDI note-on, which has the result,
that it will always sound a bit different.
and when you bounce them a few times you just can choose the best result and use it ...
that not may be taken as general recipe, but as an advice to find an own way, that you feel comfortable with ...
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