The Virus TI is a STEREO ONLY audio interface. You cannot route any audio out of outputs 3-6. They are for Virus Synth assignment output assignment only. You need another audio interface for that to work, or else all you get is a nasty feedback loop from looping input to output.
Virus TI Audio Interface = 1/2 In and 1/2 Out
Virus Synth= 1/2, 3/4, 5/6
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SH- 101, BassStation, Alesis Andromeda, Novation Nova, Virus TI 3.0.3 , ATC-1, Waldorf Blofeld... Lexicon, Line 6, Boss.... 96 Point Patchbay 
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