Its a trade off between
1) USB; no noise and low bitrate
2) ANALOG; Slight noise floor and higher bitrate.
Personally unless I am hitting a sound with massive compression the bitrate issue is a no issue. When I have used High compression on USB sound you can hear the 'zippy' truncation in the quiet parts or tails of sounds.
Consider also:
USB is sample accurate, always in time with project regardless of buffers and samplerate of project.
ANALOG outs are tight but drift a bit let's say plus or minus 3 milliseconds. It also pesents re-routing and delay miss match issues and you have to understand and calibrate your delay setting on the incoming audio.
So for least pain go for USB, and for character go for Analog.
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