Yeah, I think you can. You have to set up one of your 16 parts as an 'audio input'. You should be able to use one of the factory presets (do a search for 'input' in the browser). Once you have an input channel set up, you can apply effects, filters and I think even use the atomizer. Finally, you have the choice of routing the audio down one of the three USB's (with latency) or straight to one of the outputs. Refer to the manual regarding inputs.
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