One suggestion -- probably not what you were hoping for exactly, but it solves a lot of USB related problems and I'm surprised it's not a more popular option:
Use analog outs from the Virus to your audio interface, and use USB only for MIDI / interacting with the plugin.
Solved all my latency and USB woes. Side benefit is it sounds better than audio streaming over USB. Drawback is of course is a couple of more cables.
Benefits outweigh drawbacks.
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