Not sure what Groove is but assuming its the medium size one, that is my preference and is the size of the MKI I have. Where it matters most is your tendancy to interact with the hardware itself vs the software... I like doing some things with hardware and other things with the large screen of a computer. If you prefer to stay off the computer and deal more with the hardware, the large one is nice with the extra screens and features. The advantage of Mikro is space saving if you need that. I have mine mounted on a Roland drum stand (love it). I believe the middle sized version is the only one you can do that with, the large and small need to go on a tabletop.
I don't have a Virus keyboard, I have a Snow and use a Novation 61 key controller. My guess is controlling Komplete with the Virus would be just like any other MIDI keyboard, someone else could answer more specifically maybe.
Maschine 2.0 is the software. For example I have generation 1 hardware but I upgraded the software to 2.0 for a fee. I believe all the current hardware is generation 2 except the large model is newer. I would not be surprised if they come out with a gen 3 version sometime soon or add to the product line. Maybe new software features -- anyone's guess really.
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