Have you had any trouble loading in OS updates or the extra patches update?
Sounds like it may be a setting with-in your sequencer, but it's hard to tell from here on this side of the web. I've never tried a system reset before (as Juho mentioned), but it could help - don't know enough about that to be sure though.
The only things I can tell you is;
Make sure you have the Virus set to Force to edit buffer.
Check that your sequencer is sending sysex.
Disable out going clock.
Good luck!
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