In SER4 the filters are both in -12dB/Oct mode, connected in series, the amount of signal that goes through them is decided by filter balance.
In SER6 the filters are again serial, again the amount of signal passing through each is decided by filter balance, but in this case Filter 1 is in -24dB/Oct mode while Filter 2 is in -12dB/Oct mode.
In both of these modes saturation occurs after filter 1 and goes into filter 2.
In PAR4 mode the filters are both -12dB/oct, connected in parallel and the amount of signal is decided by filter balance. Saturation occurs after filter 1 only and the saturated signal (if any) is mixed with the output from filter 2.
In SPLIT mode the filters work as PAR4 but OSC1 and the SUB are hardwired to Filter 1 and OSC2 + Noise are hardwired to Filter 2. Saturation works like in PAR4 mode.
If you didn't get any sound, check the amount of filter balance to see which filter you're feeding and set up its cutoff frequency accordingly.
Also, I don't know about the B, but INIT patch on TI is made of 2 detuned saws, SER4, filter balance to the center with filters fully open.
You should read the manual more anyway.
There is a tutorial downloadable from the Virus main site, it's for Virus C but can be replicated with the B for the most part. There's also a diagram of the signal flow.
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