There is definitely an issue with this version and Cubase 4.5.2. Upon installing this OS version, Cubase no longer opens and constantly crashes to desktop while scanning and listin installed plugins/components. When it finishes listing the Virus Ti, Cubase immediately drops to desktop and upon looking at the Virus as this happens, the LEDS slightly flicker/dim and the words configuring Virus Ti show up on the LCD screen then disappears. It will constantly do this until I unplug power from the Virus, reboot the computer, and load Cubase without the Virus plugged in, in which it will start up without issue. Resetting the Virus with ARP Edit for 10 seconds did nothing either.
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