hey,
i found the resolution. you have to render in realtime in cubase to get rid of the weird audio stuff.
also it doesn't matter how i set my latency, it is 96 or 2048, it is always the same. the bounced audio is most of the time between 7-10 ms behind.
all for the moment i can do is to render in realtime and set the midi virus track around 7-10 ms and hope that there will be a 1.1 version of the poco virus. ... but i don't hope tho.
yes my pc is audio optimized. depends on what you mean by that. windows is a whole mess anyway

... but macs aren't any better