Did you get a new PC, or just upgrade the OS?
If the former, it sounds like something I experienced recently.
New machine - different motherboard - different USB configuration. Virus is very sensitive about sharing the USB bus with other devices, and I have quite a few - mouse + kbd, MIDI controller keyboard, MIDI interface, external HD, Maschine.
In my case, the problem was solved by plugging the Virus into a dedicated USB PCI card. See if you can get one to try out, but if not, consider just buying one. They only cost a few bucks, so even if it doesn't help, you don't lose much.
hope this helps... let us know!
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